Mortality rates and hospital discharges in Chronic Kidney Disease and Chronic Kidney Disease of non-traditional causes, Costa Rica
DOI:
https://doi.org/10.51481/amc.v58i1.907Keywords:
Chronic Kidney Disease, descriptive epidemiology, registry, Costa RicaAbstract
Aim: To characterize the evolution of Chronic Renal Failure compatible with Chronic Kidney Disease of nontraditional causes from 1990 to 2013 in Costa Rica, according to primary diagnosis of death and diagnosis at hospital discharge found in open source data bases.
Methods: A descriptive longitudinal study based on information from national data bases of deaths and hospital discharges with a primary diagnosis of chronic renal failure, unspecified renal failure, hypertensive renal disease, hypertensive cardio-renal disease from 1990 to 2013.
Results: There were 8382 deaths in Costa Rica between 1990 and 2013 in the studied categories. Crude death and standardized mortality rates did not show a significant increase: 8.93/100 000 inhabitants to 11.48/100 000 inhabitants. The specific rates by age and sex showed an increase after 50 years old. Guanacaste, showed high cumulative mortality rates compared with national and the rates of other provinces; as well as significant crude and standardized mortality rates in certain periods (20.3/100 000 inhabitants to 38.23/100 000 inhabitants between 1990 and 2011). Specific rates for age and sex increased after 30 years of age. Hospital discharges showed similar trends for national and Guanacaste.
Conclusions: Primary diagnoses of deaths and hospital discharges in the categories of the study could be compatible with Chronic Kidney Disease of non-traditional causes. Descriptive epidemiology has allowed for identification of risk geographical areas and some sociodemographic characteristics. It is urgent to develop a specific surveillance system.
Downloads
References
Wu MJ, Shu KH, Liu PH, Chiang PH, Cheng CH, Chen CH, et al. High risk of renal failure in stage 3B chronic kidney disease is under-recognized in standard medical screening. J Chin Med Assoc. 2010; 73:515-522.
Evans PD, Taal MW. Epidemiology and causes of chronic kidney disease. Medicine. 2011; 39:402-406.
Taal MW, Brenner BM. Predicting initiation and progression of chronic kidney disease: Developing renal risk scores. Kidney Int. 2006; 70:1694-1705.
Herget-Rosenthal, S., Dehnen, D., Kribben, A., & Quellmann, T. Progressive chronic kidney disease in primary care: Modifiable risk factors and predictive model. Prev Med. 2013; 57:357-362.
Satko, S., Freedman, B., & Moossavi, S. Genetic factors in end-stage renal disease. Kidney Int Suppl (2005); S46-S49.
Freedman BI. Susceptibility genes for hypertension and renal failure. J Am Soc Nephrol. 2003; 14:S192-194.
Lopes AA. Relationships of race and ethnicity to progression of kidney dysfunction and clinical outcomes in patients with chronic kidney failure. Adv Ren Replace Ther. 2004; 11:14-23.
Wickman C, Kramer H. Obesity and kidney disease: potential mechanisms. Semin Nephrol. 2013; 33:14-22.
Ejerblad E, Fored CM, Lindblad P, Fryzek J, McLaughlin JK, Nyren O. Obesity and risk for chronic renal failure. J Am Soc Nephrol. 2006; 17:1695-1702.
Meguid El Nahas A, Bello AK. Chronic kidney disease: the global challenge. Lancet. 2005; 365:331-340.
Torres C, Aragón A, González M, López I, Jakobsson K, Elinder C-G, et al. Decreased Kidney Function of Unknown Cause in Nicaragua: A CommunityBased Survey. Am J Kidney Dis. 2010; 55:485-496.
Stefanovic V, Polenakovic M, Toncheva D. Urothelial carcinoma associated with Balkan endemic nephropathy. A worldwide disease. Pathol Biol 2011; 59:286-291.
Jayatilake N, Mendis S, Maheepala P, Mehta F, Team Obot CNRP. Chronic kidney disease of uncertain aetiology: prevalence and causative factors in a developing country. BMC Nephrol. 2013; 14:180.
Karanovic S, Tomic K, Dittrich D, Borovecki F, Zavadil J, Vukovic-Lela I, et al. Endemic (Balkan) nephropathy is aristolochic acid nephropathy. Prilozi. 2014; 35:43-46.
Wijkstrom J, Leiva R, Elinder CG, Leiva S, Trujillo Z, Trujillo L, et al. Clinical and pathological characterization of mesoamerican nephropathy: a new kidney disease in central america. Am J Kidney Dis. 2013;62:908-918.
Wesseling, C., Crowe, J., Hogstedt, C., Jakobsson, K., Lucas, R., & Wegman, D. Mesoamerican nephropathy: report from the first international research workshop on men, 1 ed. Heredia: Editorial SALTRA/IRET-UNA, 2013.
Correa-Rotter R, Wesseling C, Johnson RJ. CKD of unknown origin in Central America: the case for a Mesoamerican nephropathy. Am J Kidney Dis. 2014; 63:506-520.
Almaguer M, Herrera R, Orantes CM. Chronic kidney disease of unknown etiology in agricultural communities. MEDICC Rev. 2014; 16:9-15.
Wesseling C, Crowe J, Hogstedt C, Jakobsson K, Lucas R, Wegman DH. The epidemic of chronic kidney disease of unknown etiology in Mesoamerica: a call for interdisciplinary research and action. Am J Public Health. 2013; 103:19271930.
Ramirez-Rubio O, McClean MD, Amador JJ, Brooks DR. An epidemic of chronic kidney disease in Central America: an overview. Postgrad Med J. 2013; 89:123-125.
Orantes Navarro CM, Herrera Valdes R, Lopez MA, Calero DJ, Fuentes de Morales J, Alvarado Ascencio NP, et al. Epidemiological characteristics of chronic kidney disease of non-traditional causes in women of agricultural communities of El Salvador. Clin Nephrol. 2015; 1: S24-S31.
Weiner DE, McClean MD, Kaufman JS, Brooks DR. The Central American epidemic of CKD. Clin J Am Soc Nephrol. 2013;8:504-511.
Johnson RJ, Glaser J, Sanchez-Lozada LG. Chronic kidney disease of unknown etiology: a disease related to global warming? MEDICC Rev. 2014;16:79-80.
Crowe J, van Wendel de Joode B, Wesseling C. A pilot field evaluation on heat stress in sugarcane workers in Costa Rica: What to do next? Glob Health Action. 2009;2.
Crowe J, Wesseling C, Solano BR, Umana MP, Ramirez AR, Kjellstrom T, et al. Heat exposure in sugarcane harvesters in Costa Rica. Am J Ind Med. 2013;56:1157-1164.
Robey RB. Cyclical dehydration-induced renal injury and Mesoamerican nephropathy: as sweet by any other name[quest]. Kidney Int. 2014;86:226229.
Ordunez P, Martinez R, Reveiz L, Chapman E, Saenz C, Soares da Silva A, et al. Chronic Kidney Disease Epidemic in Central America: Urgent Public Health Action Is Needed amid Causal Uncertainty. PLoS Negl Trop Dis. 2014; 8:e3019.
Jayasumana C, Paranagama P, Agampodi S, Wijewardane C, Gunatilake S, Siribaddana S. Drinking well water and occupational exposure to Herbicides is associated with chronic kidney disease, in Padavi-Sripura, Sri Lanka. Environ Health. 2015;14:6.
Jayasinghe S. Chronic kidney disease of unknown etiology should be renamed chronic agrochemical nephropathy. MEDICC Rev. 2014;16:72-74.
Jayasumana, C., Fonseka, S., Fernando, A., Jayalath, K., Amarasinghe, M., Siribaddana, S. & Paranagama, P. Phosphate fertilizer is a main source of arsenic in areas affected with chronic kidney disease of unknown etiology in Sri Lanka. Springerplus, 2015; 4:1-8.
Rosa-Diez, G., Gonzalez-Bedat, M., Pecoits-Filho, R., Marinovich, S., Fernández, S., Lugon, J, et al. Renal replacement therapy in Latin American end-stage renal disease. Clin Kidney J, 2014; sfu039.
Taming the chronic kidney disease epidemic: a global view of surveillance efforts. Kidney Int. 2014;86:246-250.
Hernández JMR, Nájera RG, Hernández CA. Comportamiento de la mortalidad por enfermedad renal crónica hipertensiva en la República Mexicana entre 1998-2009. Un problema creciente. Gac Med Mex. 2013;149:152-160.
Garcia-Garcia, G., Jha, V., Li, P. K. T., Couser, W. G., Erk, T., Zakharova, E, et al. Chronic kidney disease (CKD) in disadvantaged populations. Clin Kidney J, 2014; sfu124.
O'Donnell JK, Tobey M, Weiner DE, Stevens LA, Johnson S, Stringham P, et al. Prevalence of and risk factors for chronic kidney disease in rural Nicaragua. Nephrol Dial Transplant. 2011; 26:2798-2805.
Cerdas M. Chronic kidney disease in Costa Rica. Kidney Int Suppl. 2005; 68:S31-33.
Downloads
Published
Versions
- 2016-02-02 (3)
- 2020-07-20 (2)
- 2016-02-02 (1)
Issue
Section
License
Copyright (c) 2016 Acta Médica Costarricense

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Los autores que publican en la revista Acta Médica Costarricense pueden distribuir, copiar, remezclar, retocar, leer, descargar, imprimir, buscar y crear a partir de su obra de modo no comercial, indicando los créditos a la revista y sus autores y compartir su obra en las mismas condiciones. Para ello se aplica la licencia Creative Commons Reconocimiento-NoComercial-CompartirIgual 4.0 Internacional(CC BY-NC-SA 4.0)



