Sarcoidosis. Experience with 15 cases at the Rafael A. Calderón Guardia Hospital
DOI:
https://doi.org/10.51481/amc.v44i2.411Keywords:
Sarcoidosis, tumores del mediastino, mediastinoscopíaAbstract
Sarcoidosis is an infrequent disease in Costa Rica. In 1988the Hospital San Juan de Dios reported six cases. This is aclinical study of 15 patients diagnosed at the HospitalCalderón Guardia from 1987 to 2001. All the patientspresented with thoracic disease and in 12 of them it waslocalized to the mediastinal lymph nodes. A chest X-raydetected all the cases; cough and dispnea were the mostfrequent symptoms and mediastinoscopy was the most usefulmethod to obtain a biopsy. The histologic diagnosis wasmade in the presence of non-necrotizing granulomas, giantcells and a lymphocytic infiltrate. No microorganisms wereisolated. Fourteen patients received symptomatic treatmentand observation, and one with pulmonary disease andrespiratory symptoms received also steroids. All the patientswere observed, for an average of 7 years. They presentedspontaneous resolution without remissions.
Downloads
References
Alvarado A. Haryley L. Sarcoidosis. Acta Médica Costarricense 1988;31(1):10-19.
Hillerdal G. et al. Statement on Sarcoidosis. Am J Resp Crit Care Med.1999; 160: 735-755. 3.Newman L. Rose C. and Maier L. Sarcoidosis. N. Engl. J. Med. 1997;336:1224-1232.
Fraser R. et al. Sarcoidosis. Diagnosis of Diseases of the Chest.Saunders, Pennsylvania, 1999. Págs. 1533-1573.
Rybicki B et al. Racial diffferences in sarcoidosis incidence: a 5 yearstudy in a health maintenance organization. Am J Epidemiol 1997;145:234-241.
Buck A. Epidemiologic investigations on sarcoidosis. Am J Hyg 1961;74:189-202.
Konishi K. Molleer et al. Spontaneous expression of the IL2 receptorgene and presence of functional IL2 receptors on T lymphocytes in theblood of individuals with active pulmonary sarcoidosis. J Clin Invest1988; 82:775-781.
Agostini C. et al. Role of IL15 and IL2 and their receptors in thedevelopment of T cell alveolitis in pulmonary sarcoidosis. J Inmunol1996; 157: 910-918.
Gibson G. Prescott R. Muers M. et al. British Thoracic SocietySarcoidosis study: effects of long term corticosteroid treatment. Thorax1996; 51:238-47.
Gordis L. Sarcoidosis: Epidemiology of Chronic Lung Diseases inChildren. The John Hopkins University Press, Baltimore. 1973; 53-78.
English J. Patel P. Greer K. Sarcoidosis. J Am Acad Dermatol. 1999; 44(5): 725-43.
Kwai K. Et al. Racial difference in cardiac sarcoidosis incidenceobserved at autopsy. Sarcoidosis 1994; 11:26-31.
Milman N. Selroos. Pulmonary sarcoidosis in the Nordic countries1950-1982: epidemiology and clinical picture. Sarcoidosis 1990; 7:50-57.
Rosen Y. Sarcoidosis. In D. Dail and P. Hammer, editors. PulmonaryPathology. Springer-Verlag, New York 1994; 13-645.
Colby T. Intersticial lung diseases. In W. Thurlbeck and A. Churgeditors. Pathology of the Lund. Thieme Medical Publishers, New York1995; 589-737.
Semenzato G. et al. Redistribution of T lymphocytes in the lymphnodes of patients with sarcoidosis. N Engl J Med 1982; 306:48-49
Karma A. Ophthalmic changes in sarcoidosis. Acta Ophthalmol Suppl1979; 141:1-94.
Wilson et al. Sarcoidosis. Harrison s Principles of Internal Medicine.Mc Graw Hill, Estados Unidos. Págs. 1463-1469.
Sharma O. Cutaneous sarcoidosis: clinical features and management.Chest 1972; 61:320-325.
Maddrey W. et al. Sarcoidosis and chronic hepatic disease: a clinicaland pathology study of 20 patients. Medicine 1970; 49:375-395.
Sharma O. Vitamin D, calcium, and sarcoidosis. Chest 1996; 109:525-539.
Lofgren S. Erythema nodosum: studies on etiology and pathogenesis in185 adult cases. Acta. Med. Scand. 1996; 124:1-197.
Alsbirck P. Epidemiologic studies on sarcoidosis in Denmark based ona nationwide central register: a preliminary report. Acta Med Scand1964; 176:106-109.
Sharma O. Pulmonary sarcoidosis and corticosteroids. Am Rev Resp.Dis 1993; 147:598-600.
De Remee R. ConciseReview forPrmary-Care Physicians.Sarcoidosis. Mayo Clin Proc 1995; 70:177-181
Rybicki B.Maliarik M. Popovich J.Jr, et al: Epidemiology,demographics and genetics of sarcoidosis. Semin Respir Infect 1998;13: 166.
Douglas J. Middleton J. Gaddie G. Petrie Y. Chookang R. Prescott andCrompton. 1986. Sarcoidosis: a disorder commoner in non-smokers?Thorax 1986; 41:787-791.28. De Vuyst P. Dumortier L. Schandene M. Estenne A. Verhest andYernault. Sarcoidlike lung granulomatosas induced by aluminum dusts.Am Rev Respir Dis 1987; 135:493-497
Downloads
Published
Issue
Section
License
Copyright (c) 2008 Acta Médica Costarricense
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Los autores que publican en la revista Acta Médica Costarricense pueden distribuir, copiar, remezclar, retocar, leer, descargar, imprimir, buscar y crear a partir de su obra de modo no comercial, indicando los créditos a la revista y sus autores y compartir su obra en las mismas condiciones. Para ello se aplica la licencia Creative Commons Reconocimiento-NoComercial-CompartirIgual 4.0 Internacional(CC BY-NC-SA 4.0)
