Timely diagnosis and management of HELLP syndrome
DOI:
https://doi.org/10.51481/amc.v47i1.168Keywords:
Embarazo, hipertensión arterial, síndrome de HELLPAbstract
The HELLP syndrome of haemolysis, elevated liverenzymes and low platelets is a major complication of preg-nancy. Ten percent of pregnancies complicated by severepreeclampsia and eclampsia are affected by HELLPsyndrome.
HELLP syndrome has been described as firts appearingfrom the mid second trimester of pregnancy until severedays postpartum. Approximately one third of patients willhave their first manifestation of HELLP syndrome diag-nosed postpartum. Of the two thirds of women who are firstdiagnosed with HELLP syndrome antepartum, 10% will beidentified before 27 weeks, 20% in pregnacies beyond 37weeks, and the majority, 70%, occurring between 27 and 37weeks gestation. The maternal mortality has been reportedto be as high as 24% and perinatal mortality can range ashigh as 30-40%.
The early diagnosis and treatment of HELLP syndromeremains problematic for the obstetric health care provider.The non-especific signs and symptoms of this disorder earlyin the disease process make the accurate diagnosis difficultand delays early treatment, which has the best prognosis forboth maternal and perinatal outcome. The management of thepregnancy complicated by HELLP syndrome requires earlyrecognition and the institution of the appropriate therapy.
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