Epidemiological Behavior of Hansen’s Disease in Costa Rica, 2018-2022
DOI:
https://doi.org/10.51481/amc.v65i4.1361Keywords:
leprosy, epidemiology, neglected diseases, Costa RicaAbstract
Objective: To describe the epidemiological characteristics of leprosy in Costa Rica from 2018-2022.
Methods: Retrospective observational descriptive study from 2018 to 2022 of Hansen’s Disease cases using individual notification records under the International Classification of Diseases 10th Revision. To determine the number of new cases, anonymized information was requested from the Epidemiology Unit of the Costa Rican Social Security Fund and the Epidemiology Unit of the Health Surveillance Directorate of the Ministry of Health.
Results: In Costa Rica, between 2018-2022, 50 cases of Hansen’s disease were registered (annual average of 10). The mean age at diagnosis was 48.46 ± 17.88 years for the group in general, with an age range between 15 -78 years. The sex ratio (male/female) was 2.33 (15/35). The province of Puntarenas recorded 26 cases (52%). The canton of Garabito registered a prevalence rate at the subnational level of more than 1 per ten thousand inhabitants. No cases in children under 15 years of age were reported. The overall mean leprosy detection rate during the study period was 0.2 (50/25 549 059) per 100000 population. The leprosy detection rate decreased from 0.26 (13/5,003,402) to 0.249 (8/5213374) per 100000 population between 2018 and 2022. The proportion of cases classified as multibacillary leprosy increased by 100% in 2019. The proportion of leprosy in women decreased from 38.46% to 12.5%.
Conclusion: Nationwide, the disease prevalence is maintained at elimination levels. However, at the subnational level, districts with rates higher than 1 per 10000 inhabitants still exist.
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References
Cardona-Castro N, Escobar-Builes MV, Serrano-Coll H, Adams LB, Lahiri R. Mycobacterium lepromatosis as Cause of Leprosy, Colombia. Emerg Infect Dis. 2022;28:1067-8. DOI: 10.3201/eid2805.212015
Froes LAR Junior, Sotto MN, Trindade MAB. Leprosy: clinical and immunopathological characteristics. An Bras Dermatol. 2022 May-Jun;97:338-347. DOI: 10.1016/j.abd.2021.08.006
Somar P, Waltz MM, van Brakel WH. The impact of leprosy on the mental wellbeing of leprosy-affected persons and their family members - a systematic review. Glob Ment Health (Camb). 2020;7: e15. DOI: 10.1017/gmh.2020.3
Santacroce L, Del Prete R, Charitos IA, Bottalico L. Mycobacterium leprae: A historical study on the origins of leprosy and its social stigma. Infez Med. 2021;29:623-32. DOI: 10.53854/liim-2904-18
Ghosh S, Chaudhuri S. Chronicles of Gerhard-Henrik Armauer Hansen's Life and Work. Indian J Dermatol. 2015;60:219-21. DOI: 10.4103/0019-5154.156310
Sakai T, Morimoto Y. The History of Infectious Diseases and Medicine. Pathogens. 2022;11:1147. DOI: 10.3390/pathogens11101147
Noordeen SK. 4. Epidemiology and control of leprosy—a review of progress over the last 30 years. Transactions of the Royal Society of Tropical Medicine and Hygiene. 1993;87:515-7. DOI :10.1016/0035-9203(93)90068-2
The Lancet Infectious D. Leprosy elimination not yet in sight. The Lancet Infectious Diseases. 2005;5:321. DOI: 10.1016/S1473-3099(05)70117-1
Blok DJ, De Vlas SJ, Richardus JH. Global elimination of leprosy by 2020: are we on track? Parasit Vectors. 2015;8(1):548. DOI: 10.1186/s13071-015-1143-4
Jariyakulwong N, Julanon N, Saengboonmee C. Lepromatous leprosy with a suspected 30-year incubation period: A case report of a practically eradicated area. J Taibah Univ Med Sci. 2022;17: 602-605. DOI: 10.1016/j.jtumed.2021.12.005
Rodrigues LC, Lockwood DNJ. Leprosy now: epidemiology, progress, challenges, and research gaps. Lancet Infect. Dis. 2011;11:464-70. DOI: 10.1016/S1473-3099(11)70006-8
Rivera Chavarría A, Sánchez Hernández G, Espinoza Aguirre A. Afectación familiar de la enfermedad de Hansen en Costa Rica. Acta med. costarric 2021;63:5-13. DOI: 10.51481/amc.v63i1.1146
Flores Sandí G, Rivera Chavarría AL, Solano Calderón P. TEMA-2017: Enfermedad de Hansen: A propósito de un Caso Médico Legal. Rev. clín. esc. med. UCR-HSJD. 2017;7:1-6. DOI: 10.15517/rc_ucr-hsjd.v7i6.31941
Rivera A, Espinoza A. Comportamiento epidemiológico de la lepra en Costa Rica, de 2012 al 2017. Rev. clín. esc. med. UCR-HSJD. 2018;8:32-36.
Sharma R, Singh P, McCoy RC, Lenz SM, Donovan K, Ochoa MT, et al. Isolation of Mycobacterium lepromatosis and Development of Molecular Diagnostic Assays to Distinguish Mycobacterium leprae and M. lepromatosis. Clin Infect Dis. 2020 Nov 5;71: e262-e269.DOI: 10.1093/cid/ciz1121. PMID: 31732729; PMCID: PMC8189713.
Butlin CR, Lockwood DNJ. Changing proportions of paucibacillary leprosy cases in global leprosy case notification. Lepr Rev. 2020;91:255-61. DOI: 10.47276/lr.91.3.255
Gnimavo RS, Djossou P, Sopoh GE, Anagonou GE, Barogui YT, Wadagni AAC, et al. Trends of the leprosy control indicators in Benin from 2006 to 2018. BMC Public Health. 2020; 20:1254. DOI: 10.1186/s12889-020-09341-w
Espinoza Aguirre A. Prevalencia de lepra en Costa Rica, de 1998-2003. Rev. costarric. salud pública. 2007;16:36-41.
Ramos JM, Martínez-Martín M, Reyes F, Lemma D, Belinchón I, Gutiérrez F. Gender differential on characteristics and outcome of leprosy patients admitted to a long-term care rural hospital in South-Eastern Ethiopia. Int J Equity Health. 2012;11:56. DOI: 10.1186/1475-9276-11-56
Nobre ML, Illarramendi X, Dupnik KM, Hacker MA, Nery JA, Jerônimo SM, et al. Multibacillary leprosy by population groups in Brazil: Lessons from an observational study. PLoS Negl Trop Dis. 2017;11: e0005364. DOI: 10.1371/journal.pntd.0005364
Arunraghav P, Herakal K. Leprosy in Elderly and Children among New Cases - A 3-Year Retrospective Study. Indian Dermatol Online J. 2021;12:294-7. DOI: 10.4103/idoj.IDOJ_177_18
Kumar A, Girdhar A, Girdhar BK. Incidence of leprosy in Agra district. Lepr Rev. 2007;78:131-136.
Pescarini JM, Strina A, Nery JS, Skalinski LM, Andrade KVF, Penna MLF, et al. Socioeconomic risk markers of leprosy in high-burden countries: A systematic review and meta-analysis. PLoS Negl Trop Dis. 2018;12: e0006622.DOI: 10.1371/journal.pntd.0006622
Sanchez MN, Nery JS, Pescarini JM, Mendes AA, Ichihara MY, Teixeira CSS, et al. Physical disabilities caused by leprosy in 100 million cohort in Brazil. BMC infectious diseases. 2021;21:290. DOI: 10.1186/s12879-021-05846-w
Penna ML, de Oliveira ML, Penna GO. The epidemiological behaviour of leprosy in Brazil. Lepr Rev. 2009;80:332-44.
Son AM. A woman with leprosy is in double jeopardy. Lepr Rev. 2000;71:128-43. DOI: 10.5935/0305-7518.20000016
Oliveira MB, Diniz LM. Leprosy among children under 15 years of age: literature review. An Bras Dermatol. 2016;91:196-203. DOI: 10.1590/abd1806-4841.20163661
Moraes PC, Eidt LM, Koehler A, Pagani DM, Scroferneker ML. Epidemiological characteristics and trends of leprosy in children and adolescents under 15 years old in a low-endemic State in Southern Brazil. Rev Inst Med Trop Sao Paulo. 2021;63: e. DOI: 10.1590/S1678-9946202163
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