Soy protein: Non-pharmacological alternative for the treatment of children with hypercholesterolemia
DOI:
https://doi.org/10.51481/amc.v46i1.131Keywords:
niños con hipercolesterolemia, proteína de soya, dieta, LDL-CAbstract
Soybean Protein: A non- pharmacological alternative for the treatment of children with hypercholesterolemia
Primary hypercholesterolemia treatment (PHT) is based on a reduced diet in saturated fat and cholesterol, which can diminish between 10 and 20% of serum cholesterol (CT). Soy-bean protein has the potential to reduce CT, when it substitu-tes partial or totally animal protein. The present study shows the results of the effect of a low saturated fat, cholesterol and soybean protein diet on LDL-C in Costa Rican children with primary hypercholesterolemia.
Twenty children, between the ages of 7 and 14, were ran-domly assigned to one of the two dietary treatments at home. The experimental group received: Stage 1 NCEP diet, it con-sisted of 25 more grams of soybean protein and the control group received: Stage 1 NCEP diet without soybean protein. After a homogenization period of ten days, the intervention began for eight weeks.
Both groups reduced their total cholesterol and their LDL-C (p< 0,05). However, the experimental group showed a greater reduction of their LDL-C (10,5 % vs. 3,9 %l), than the control, but this difference was not significant. Those who consumed more than 20 grams of soybean protein had a bigger reduction of their LDL-C and a smaller negative effect of their HDL-C.
Soy protein diet did not have significant effect on LDL-C reduction. We can not conclude that there is an advantage of using soy protein over traditional treatment of primary hypercholesterolemia.
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