Radiotherapy in pediatric patients with acute lymphocytic leukemia: a 9-year experience
DOI:
https://doi.org/10.51481/amc.v64i4.1242Keywords:
Radiotherapy, acute lymphocytic leukemia, pediatric, epidemiology, treatmentAbstract
Aim: To describe the epidemiological and clinical characteristics of patients with acute lymphocytic leukemia, attended at the National Children´s Hospital ""Dr. Carlos Sáenz Herrera"" that received external radiation therapy between January 2009 and December 2017.
Methods: It is an observational, descriptive study. Clinical records of pediatric patients (0-13 years) with acute lymphoblastic leukemia that received external radiotherapy in the study period were retrospectively reviewed. A descriptive statistical analysis of the qualitative and quantitative variables was applied.
Results: 58 patients were studied, 79,3% were males. The mean age was 7,3 years. 84,2% were classified as L1, 84,2% had common B immunophenotype and 56,9% were in the high risk group at diagnosis. The main indication for radiotherapy was relapse (67,7%). About half the patients received radiotherapy to central nervous system and the other half to testicles. The main side effects were cutaneous.
Conclusions: The results obtained were comparable to those seen in literature. Radiotherapy is important in leukemia treatment, particularly in relapse and high risk patients.
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