Double heterozygous patient for New York Hemoglobin (HB Kaohsiung) and Alpha Thalassemia (-α3.7/αα)
DOI:
https://doi.org/10.51481/amc.v63i2.1195Keywords:
hemoglobin New York, hemoglobin Kaohsiung, alpha thalassemia, red cells indices, anemiaAbstract
An asymptomatic adult female, with no previous family history of anemia or chronic diseases, goes to consultation at Aserrí ´s Clínic for anemia follow up. A history review of the medical record shows that MCV is below the lower reference range. This MCV value induces the physician to treat the patient for iron deficiency anemia.
Using the algorithm of the Clinical Laboratory in Aserrí, such erythrocytic indices are suggestive of Thalassemia. For these reason a blood sample is sent for hemoglobin electrophoresis and molecular analysis at the specialized hematology laboratory at the National Children´s Hospital. A variant hemoglobin is detected.
To our knowledge, this is the first case of compound heterozygous for Hemoglobin New York/-3.7 Alfa Thalassemia in Costa Rica.
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