Case series of liver transplantation in ""Dr. Rafael Ángel Calderón Guardia Hospital""

Authors

  • Claudia Catarinella-Gómez Caja Costarricense de Seguro Social, Hospital ""Dr. Rafael Ángel Calderón Guardia"", Costa Rica
  • Vanessa López Jara Caja Costarricense de Seguro Social, Hospital ""Dr. Rafael Ángel Calderón Guardia"", Costa Rica
  • Sheyla Araya Chavarría Caja Costarricense de Seguro Social, Hospital ""Dr. Rafael Ángel Calderón Guardia"", Costa Rica
  • Mario Sánchez Arias Caja Costarricense de Seguro Social, Hospital ""Dr. Rafael Ángel Calderón Guardia"", Costa Rica
  • Marietta Dailey Araya Caja Costarricense de Seguro Social, Hospital ""Dr. Rafael Ángel Calderón Guardia"", Costa Rica
  • María del Rosario Espinoza Mora Universidad de Costa Rica, Costa Rica.

DOI:

https://doi.org/10.51481/amc.v63i1.1149

Keywords:

transplant, liver transplant, solid organ transplant, immunosuppression, liver

Abstract

Objective: To analyze the outcomes, most frequent complications and characteristics of the patients enrolled in the Liver Transplant Program from the Hospital ""Dr. Rafael Ángel Calderón Guardia"".

Methods: This is a retrospective investigation that involves the revision of clinical records from the patients that received a liver transplant between the years 2009 and 2018 in the Hospital ""Dr. Rafael Ángel Calderón Guardia"". The following variables were considered: age, gender, nationality, city of residence, manifestations of the liver disease, reason for the liver transplant, clinical outcomes after transplant, comorbidities, medication received, important laboratory results and biopsies. The data analysis was performed with STATA, using a statistic significance threshold of a p < 0.05.

Results: The sample was composed of a total of 45 liver transplant surgeries and 44 patients who received a liver transplant between the years 2009 and 2018. The patients mostly came from the city of San José. The average age at the time of the surgery was 51 years. The most common liver disease that led to transplant was alcoholic cirrhosis, followed by NASH and cryptogenic cirrhosis. The most common complications of the liver disease documented prior to transplant where esophageal varices, gastrointestinal bleeding and hepatic-renal syndrome. 10 of the patients included in the study died, which corresponds to 22.7% of the sample.

Conclusions: The mortality observed in the liver transplant cases analyzed was 22.7%, most of the cases were taken to transplantation due to liver disease related to alcoholic cirrhosis, steatohepatitis and cryptogenic cirrhosis.

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Published

2021-07-14

How to Cite

Case series of liver transplantation in ""Dr. Rafael Ángel Calderón Guardia Hospital"". (2021). Acta Médica Costarricense , 63(1), 21-28. https://doi.org/10.51481/amc.v63i1.1149