Rheumatoid vasculitis: about two cases)

Authors

  • Marvin Sánchez Benavides Caja Costarricense del Seguro Social, Hospital Dr. Rafael A. Calderón Guardia

DOI:

https://doi.org/10.51481/amc.v60i2.1001

Keywords:

rheumatoid vasculitis, rheumatoid arthritis, extra-articular manifestations

Abstract

Rheumatoid vasculitis remains a rare but serious complication of rheumatoid arthritis characterized by an inflammatory process that primarily affects small to medium-sized blood vessels, it can be associated with other extra-articular manifestations. A number of predictor or predisposing factors including certain human leukocyte antigen haplotypes, smoking and long-standing disease. A declining trend in the incidence of rheumatoid vasculitis

has been noted since the 1990s and reconfirmed in recent studies, related to early diagnosis of rheumatoid arthritis, and widespread use of methotrexate. Rheumatoid vasculitis is associated with high rates of premature mortality with up to 40% of patients dying by 5 years, as well as a significant morbidity. We present two patients with diagnosis of rheumatoid arthritis with a chronic condition of ulcers and dysesthesias on legs associated with anemic syndrome; the histological study revealed medium size vasculitis. Treatment with inmunosuppresants and steroids was given with resolution of symptoms.

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References

Makol A, Matteson EL, Warrington KJ. Rheumatoid vasculitis: an update. Curr Opin Rheumatol 2015,27:63-70

Gorman DJ, David-Vaudey E, Pai M, Lum RF, Criswell LA. Particular HLADRB1 shared epitope genotypes are strongly associated with rheumatoid vasculitis. Arthritis Rheum 2004;50:3476-3484

Watts RA, Mooney J, Lane SE, Scott DGI. Rheumatoid vasculitis: becoming extint. Rheumatology (Oxford) 2004;43:920-923

Genta MS, Genta RM, Gabay C. Systemic Rheumatoid Vasculitis: A review. Semin Arthritis Rheum 36:88-98,2006

Ntatsaki EM, Mooney J, Scott DGI, Watts RA. Systemic rheumatoid vasculitis in the era of modern immunosuppressive therapy. Rheumatology 2014;53:145152

Makol A, Crowson CS, Wetter DA, Sokumbi O, Matteson EL, Warrington KJ. Vasculitis associated with rheumatoid arthritis: a cae-control study. Rheumatology (Oxford) 2014;53:890-899

Matsunawa M, Isozaki T, Osai T, Yajima N, Takeuchi HT, Negishi M et al. Increased serum levels of soluble fractalkine (CX3CL1) correlated with disease activity in rheumatoid vasculitis. Arthritis Rheum. 2006;54:3408-3416

Tago M, Naito Y, Aihara H, Furkawa N, Yamashita S. Recurrent stenosis of the ileum caused by rheumatoid vasculitis. Intern Med. 2016;55(7):819-823

Voskuyl AE, Hazes JmW, Zwinderman AH, Paleolog EM, van deer Meer FJM et al. Diagnostic strategy for the assessment of rheumatoid vasculitis. Ann Rheum Dis 2003;62:407-413

Watts, RA. Rheumatoid vasculitis-down but not out. Nat. Rev. Rheumatol. 10,281-282 (2014).

Instrucciones para autores

Parker B, Chattopadhyay C. A case of rheumatoid vasculitis involving the gastrointestinal tract in early disease. Rheumatology (Oxford) 2007;46:17371738

Published

2018-05-03 — Updated on 2018-05-03

Versions

How to Cite

Rheumatoid vasculitis: about two cases). (2018). Acta Médica Costarricense , 60(2), 34-37. https://doi.org/10.51481/amc.v60i2.1001