Dolor óseo inducido por cáncer metastático: Fisiopatología y Tratamiento
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https://doi.org/10.51481/amc.v46i1.128Palabras clave:
Dolor, metastásico, óseo, revisiónResumen
Se estima que de un 60 a 84% de los pacientes con cáncer desarrollan metástasis óseas. De estos un 70% experimentan síndromes dolorosos de difícil manejo, de los cuales un 50% muere sin un adecuado alivio del dolor con una pobre calidad de vida. Por tanto, es necesario contar con medicamentos accesibles y efectivos para el manejo de esta patología…..
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Payne R. Mechanisms and management of bone pain. American Cancer Society. Magazine supplement: Skeletal complications of malignancy 1997; 80: 16081613.
Cleeland CS, Gonin R, Hatfield AK, Edmonson JH, Blum RH, Stewart JA et. al. Pain and its treatment in outpatients with metastasic cancer. N Engl J Med 1994; 6: 592596.
Honore P, Luger N, Sabino M, Schwei MJ, Rogers S, Mach D, et. al. Osteoprotegerin blocks bone cancerinduced skeletal pain and painrelated neurochemical changes in spinal cord. Nature 2000; 5: 521528.
Regan J, Peng P. Neurophysiology of cancer pain. Cancer Control magazine 2000; 7: 111119
OMS. Palliation of bone pain in cancer: Facts and controversies report 2002; 15: 46.
Goltzman D. Mechanism of the Development of Osteoblastic Metastases. Magazine Supplement: Skeletal Complications of Malignancy. Cancer 1997; 80: 15811587
Markman M. Clinical Trials in Oncology. En: Markman M. ed. Basic Cancer Medicine. Philadelphia: W. B. Saunders, 1997: 1113
Sabino M, Ghilardi J, Feia K. The involment of prostaglandins in tumorogenesis, tumor induced osteolysis and bone cancer pain. J Musc skel Neur Interact 2002; 2: 562561.
Meyer R, Campbell J, Raja S. Peripheral neural mechanisms of nociception. En: Wall P, Melzack R. ed. Textbook of pain. Londres: Churchil Livingstone, 1994: 1314.
Fontana A, Delmas P. Markers of bone turnover in bone metastases. Magazine Supplement: Skeletal Complications of malignancy. Cancer 2000; 88: 29522960
Raja S, Meyer J, Meyer R. Peripheral mechanism of somatic pain. Anestesiology 1988; 68: 571590.
Schimdt R, Scable H, Messlinger K, Heppelmann B, Hanesh U, Pawlak M. Silent and active nociceptors: Structure, functions and clinical implications. En: Gebhart G, Hammond D, Jensen T. eds. Progress in pain research and management. Seattle: IASP press, 1994; 2: 213250.
Niv D, Devor M. Analgesia preventiva: Se puede prevenir el dolor posoperatorio agudo? En: Abrahms B, Benzon H, Hanh M, Heaver J, Niv D, Parris W. et. al. eds. Tratamiento Práctico del Dolor. España: Harcout Brace, 2000: 10431044.
Woolf C. Evidence of a central component of post injury pain hypersensitivity. Nature 1984; 308: 686688.
Woolf C, Thompson S. The induction and maintenance of central sensibilization is dependent on NmethylDaspartic acid receptor activation: Implications for treatment of postinjury pain hypersensitivity states. Pain magazine 1991; 44: 293299.
Niv D, Devor M. Transition from acute to chronic pain. En: Arnoff G. ed. Evaluation and treatment of Chronic Pain. Baltimore: William & Wilkins, 1998: 2745
Willis W. Hiperalgesia and allodynia. New Cork: Raven Press, 1992: 230234
Mercante S. Malignant Bone Pain: Pathophisiology and treatment. Pain magazine 1997; 69: 118.
Mauskop A, Foley K. Control of Pain. En: Harrington K. ed. Orthopedic management of methastasic bone disease. St. Louis: Mosby, 1998: 455460.
Twycross R. Measurement of pain. En: Twycross R. Ed. Pain Relief in Advanced Cancer. Londres: Churchill Livingstone, 1994: 129147.
Barnard D, McGarrity S. Cuidados paliativos. En: Abrahms B, Benzon H, Hanh M, Heaver J, Niv D, Parris W. et. al. ed. Tratamiento Práctico del Dolor. España: Harcout Brace, 2000: 881902.
Doleys D, Doherty D. Evaluación piscológica y conductual. En: Abrahms B, Benzon H, Hanh M, Heaver J, Niv D, Parris W. et. al. ed. Tratamiento Práctico del Dolor. España: Harcout Brace, 2000: 429448.
Sykes F, Johnson R, Hanks G. Difficult pain problems. En: Fallon M. O Neill B. eds. ABC of Palliative Care. Londres: BMJ Books, 1998: 67
Wizenberg M. The philosophy and economics of palliative radiotherapy for bone metastases. En; Wiess L, Gilbert H. ed. Bone Metastases. Boston: Hall, 1981: 330398.
Coia L, Hanks G, Martz K. Practice patterns of palliative care in United States. 19841985. Int J Radiat Oncol Biol Phys 1988; 14: 12611269.
Ashby M. Radiotherapy in the Palliation of Cancer. En: Patt R. Ed. Cancer Pain. Philadelphia: Lippincott Co, 1993: 235249
Stein C. The control of pain in peripheral tissues by opioids. N Eng J Med 1995; 332: 168590.
Alastair J. Wood J. Pharmacologic treatment of cancer pain. N Eng J Med 1996; 335: 11241131.
Bruera E. Anorexia, Cachexia and Nutrition. En: Fallon M. O Neill B. eds. ABC of Palliative Care. Londres: BMJ Books, 1998: 1922.
Rogers M, Gordon S, Benford H. Coxon F, Luckman S, Monkkonen J. et. al. Cellular and Molecular Mechanism of action of biphosphonates. American Cancer Society. Magazine Supplement: Skeletal Complications of Malignancy 2000; 88: 29612978.
Smith J. Oncologic Emergencies. En: Patt R. ed. Cancer Pain. Philadelphia: Lippincott Co, 1993: 527541.
Serafini A. Samarium Sm153 Lexidoram for the palliation of bone Pain Associated with Metastases. American Cancer Society. Magazine Supplement: Skeletal Complications of Malignancy 2000; 88: 29342939.
Swerdlow M. Role of Chemical neurolysis and local anesthesic infiltration. En: Swerdlow M, Ventafridda V. ed. Cancer Pain. Londres: Editorial MTP, 1987: 119122.
Hofbauer L, Neubauer A, Heufelder A. Receptor Activator of Nuclear Factor -B Ligand and Osteoprotegerin. Cancer 2001; 93: 460470.
Priest J. Metastasic Cancer Pain. En: Ramamurthy S, Rogers J. eds. Pain Management. Londres: Mosby Year Book, 1990: 5455
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