Toxicidad cutánea a corto plazo de pacientes con cáncer de mama tratados con radioterapia hipofraccionada

Autores/as

  • Rolando Loría Ruíz Instituto Oncológico del Sureste
  • Rafael Lengua Reyes Instituto Oncológico del Sureste
  • Erick Palacios García Instituto Oncológico del Sureste
  • Adriana Fondevilla Soler Instituto Oncológico del Sureste

DOI:

https://doi.org/10.51481/amc.v55i4.813

Palabras clave:

cáncer de mama, hipofraccionamiento, radioterapia

Resumen

Antecedentes: reportar la factibilidad y resultados de toxicidad cutánea en una cohorte de pacientes portadores de cáncer de mama, tratados con un esquema de hipofraccionamiento de radioterapia externa, con un manejo multidisciplinario.Métodos: utilizando un software SPSS v18, se realizó un análisis retrospectivo de 299 pacientes (6 H y 293 M), tratados entre marzo de 2009 y diciembre de 2011, en el Instituto Oncológico del Sureste, Murcia, España. La mediana de edad fue de 54 años (rango, 31-89); 145 (48,49%) pacientes con cáncer de mama derecha y 154 (51,50%) de mama izquierda. Con base en la 7ª ed AJCC, la etapificaciónpatológica fue: 118 (39,5%) pacientes T1, 114 (38,1%) T2, 43 (14,1%) T3, 11 (3,8%) T4, 5 (1,7%) Tis, 4 (1,3%) Tx; 137 pacientes (45,8%) eran N0, 94 (31,5%) N1, 45 (15%) N2, 20 (6,70%) N3 y 3 (1,00%) Nx. Todos los pacientes se sometieron a RTE con técnica 3D conformada con esquema hipofraccionado de 2,67 Gy/día, en 15 fracciones para una dosis total de 40.05 Gy. Se realizó irradiación electiva a la región supraclavicular en 169 pacientes, con igual fraccionamiento. El 100% de la muestra se sometió a cirugía, el 84,3% recibió quimioterapia (66,21% postoperatoria y 18,1% neoadyuvante).Resultados: sesenta y siete pacientes (23,1%) presentaron toxicidad cutánea grado 2 al finalizar el tratamiento. No se reportó toxicidad cutánea aguda severa.Conclusión: el esquema de hipofraccionamiento empleado en cáncer de mama es factible y no ha demostrado incremento en la toxicidad aguda severa a nivel de piel.

Citas

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Publicado

2013-10-21 — Actualizado el 2013-10-21

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Cómo citar

Ruíz, R. L., Reyes, R. L., García, E. P., & Soler, A. F. (2013). Toxicidad cutánea a corto plazo de pacientes con cáncer de mama tratados con radioterapia hipofraccionada. Acta Médica Costarricense , 55(4), 176-181. https://doi.org/10.51481/amc.v55i4.813