Enfermedad de Castleman. Reporte de 14 casos de 1990-2002 en el Hospital "Dr. Rafael A. Calderón Guardia", dos con presentación inusual y revisión de literatura

Autores/as

  • Eduardo Fiedler Velásquez Caja Costarricense del Seguro Social, Hospital Dr. Rafael A. Calderón Guardia
  • Charles Gourzong Taylor Caja Costarricense del Seguro Social, Hospital Dr. Rafael A. Calderón Guardia
  • Pedro Goyenaga Hernández Caja Costarricense del Seguro Social, Hospital Dr. Rafael A. Calderón Guardia
  • Jairo López Castro Caja Costarricense del Seguro Social, Hospital Dr. Rafael A. Calderón Guardia

DOI:

https://doi.org/10.51481/amc.v47i3.194

Palabras clave:

enfermedad de Castleman, trastorno linfoproliferativo, comportamientoclínico

Resumen

La enfermedad de Castleman (hamartoma linfoideo, linfoma gigante benigno, hiperplasia angiofolicular de los nódulos linfáticos) es un transtorno linfoproliferativo raro, de curso usualmente benigno de etiología desconocida y pobremente entendido. Resulta de un crecimiento no regulado del tejido linfático y puede manifestarse clínicamente en 2 formas, localizada y diseminada o multicéntrica, con 3 variantes histopatológicas, vascular hialino, plasmocelular y mixto o transicional. Usualmente la forma vascular hialina tiene una evolución clínica benigna manifestada solamente por adenopatías, en cambio, la forma plasmocelular o mixta puede manifestar alteraciones físicas y de laboratorio, tales como fiebre, pérdida de peso, anemia e hiperglobulinemia. Las 2 últimas condiciones clínicas pueden resultar en transformación maligna similar al linfoma de Hodgkin. Revisamos la base de datos del Servicio de Patología de nuestro hospital y encontramos 14 casos reportados desde enero de 1990 hasta enero del 2002, 2 mostraron presentación inusual

Citas

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Publicado

2005-07-01

Cómo citar

Fiedler Velásquez, E., Gourzong Taylor, C., Goyenaga Hernández, P., & López Castro, J. (2005). Enfermedad de Castleman. Reporte de 14 casos de 1990-2002 en el Hospital "Dr. Rafael A. Calderón Guardia", dos con presentación inusual y revisión de literatura. Acta Médica Costarricense, 47(3), 137–143. https://doi.org/10.51481/amc.v47i3.194